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ALDH1 expression predicts progression of premalignant lesions to cancer in Type I endometrial carcinomas

In type 1 endometrial cancer, unopposed estrogen stimulation is thought to lead to endometrial hyperplasia which precedes malignant progression. Recent data from our group and others suggest that ALDH activity mediates stemness in endometrial cancer, but while aldehyde dehydrogenase 1 (ALDH1) has be...

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Detalles Bibliográficos
Autores principales: Mah, Vei, Elshimali, Yahya, Chu, Alison, Moatamed, Neda A., Uzzell, Jamar P., Tsui, Jessica, Schettler, Stephen, Shakeri, Hania, Wadehra, Madhuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184965/
https://www.ncbi.nlm.nih.gov/pubmed/34099751
http://dx.doi.org/10.1038/s41598-021-90570-3