Chemical combinations potentiate human pluripotent stem cell-derived 3D pancreatic progenitor clusters toward functional β cells

Human pluripotent stem cell (hPSC)-derived pancreatic β cells are an attractive cell source for treating diabetes. However, current derivation methods remain inefficient, heterogeneous, and cell line dependent. To address these issues, we first devised a strategy to efficiently cluster hPSC-derived...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Haisong, Li, Ronghui, Liao, Hsin-Kai, Min, Zheying, Wang, Chao, Yu, Yang, Shi, Lei, Dan, Jiameng, Hayek, Alberto, Martinez Martinez, Llanos, Nuñez Delicado, Estrella, Izpisua Belmonte, Juan Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184986/
https://www.ncbi.nlm.nih.gov/pubmed/34099664
http://dx.doi.org/10.1038/s41467-021-23525-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184986/
https://www.ncbi.nlm.nih.gov/pubmed/34099664
http://dx.doi.org/10.1038/s41467-021-23525-x

Ejemplares similares