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A metabolic modeling approach reveals promising therapeutic targets and antiviral drugs to combat COVID-19

In this study we have developed a method based on Flux Balance Analysis to identify human metabolic enzymes which can be targeted for therapeutic intervention against COVID-19. A literature search was carried out in order to identify suitable inhibitors of these enzymes, which were confirmed by dock...

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Detalles Bibliográficos
Autores principales: Santos-Beneit, Fernando, Raškevičius, Vytautas, Skeberdis, Vytenis A., Bordel, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184994/
https://www.ncbi.nlm.nih.gov/pubmed/34099831
http://dx.doi.org/10.1038/s41598-021-91526-3