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A metabolic modeling approach reveals promising therapeutic targets and antiviral drugs to combat COVID-19
In this study we have developed a method based on Flux Balance Analysis to identify human metabolic enzymes which can be targeted for therapeutic intervention against COVID-19. A literature search was carried out in order to identify suitable inhibitors of these enzymes, which were confirmed by dock...
Autores principales: | Santos-Beneit, Fernando, Raškevičius, Vytautas, Skeberdis, Vytenis A., Bordel, Sergio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8184994/ https://www.ncbi.nlm.nih.gov/pubmed/34099831 http://dx.doi.org/10.1038/s41598-021-91526-3 |
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