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ER-mitochondria contact sites in neurodegeneration: genetic screening approaches to investigate novel disease mechanisms
Mitochondria-ER contact sites (MERCS) are known to underpin many important cellular homoeostatic functions, including mitochondrial quality control, lipid metabolism, calcium homoeostasis, the unfolded protein response and ER stress. These functions are known to be dysregulated in neurodegenerative...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185109/ https://www.ncbi.nlm.nih.gov/pubmed/33335290 http://dx.doi.org/10.1038/s41418-020-00705-8 |