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ER-mitochondria contact sites in neurodegeneration: genetic screening approaches to investigate novel disease mechanisms

Mitochondria-ER contact sites (MERCS) are known to underpin many important cellular homoeostatic functions, including mitochondrial quality control, lipid metabolism, calcium homoeostasis, the unfolded protein response and ER stress. These functions are known to be dysregulated in neurodegenerative...

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Detalles Bibliográficos
Autores principales: Wilson, Emma Louise, Metzakopian, Emmanouil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185109/
https://www.ncbi.nlm.nih.gov/pubmed/33335290
http://dx.doi.org/10.1038/s41418-020-00705-8