Cargando…

Recurrent emergence of SARS-CoV-2 spike deletion H69/V70 and its role in the Alpha variant B.1.1.7

We report severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike ΔH69/V70 in multiple independent lineages, often occurring after acquisition of receptor binding motif replacements such as N439K and Y453F, known to increase binding affinity to the ACE2 receptor and confer antibody escape...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meng, Bo, Kemp, Steven A., Papa, Guido, Datir, Rawlings, Ferreira, Isabella A.T.M., Marelli, Sara, Harvey, William T., Lytras, Spyros, Mohamed, Ahmed, Gallo, Giulia, Thakur, Nazia, Collier, Dami A., Mlcochova, Petra, Duncan, Lidia M., Carabelli, Alessandro M., Kenyon, Julia C., Lever, Andrew M., De Marco, Anna, Saliba, Christian, Culap, Katja, Cameroni, Elisabetta, Matheson, Nicholas J., Piccoli, Luca, Corti, Davide, James, Leo C., Robertson, David L., Bailey, Dalan, Gupta, Ravindra K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185188/ https://www.ncbi.nlm.nih.gov/pubmed/34166617 http://dx.doi.org/10.1016/j.celrep.2021.109292

Ejemplares similares

SARS-CoV-2 B.1.1.7 sensitivity to mRNA vaccine-elicited, convalescent and monoclonal antibodies
por: Collier, Dami A., et al.
Publicado: (2021)

Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies
por: Collier, Dami A., et al.
Publicado: (2022)

Production of Recombinant Replication-defective Lentiviruses Bearing the SARS-CoV or SARS-CoV-2 Attachment Spike Glycoprotein and Their Application in Receptor Tropism and Neutralisation Assays
por: Thakur, Nazia, et al.
Publicado: (2021)

The origins and molecular evolution of SARS-CoV-2 lineage B.1.1.7 in the UK
por: Hill, Verity, et al.
Publicado: (2022)

SARS-CoV-2 evolution during treatment of chronic infection
por: Kemp, Steven A, et al.
Publicado: (2021)

Performance Evaluation of the SAMBA II SARS-CoV-2 Test for Point-of-Care Detection of SARS-CoV-2
por: Assennato, Sonny M., et al.
Publicado: (2020)

Fission of $^{27}$Al nucleus by 69-MeV monochromatic photons
por: Tavares, O A P, et al.
Publicado: (1993)

No evidence of SARS-CoV-2 reverse transcription and integration as the origin of chimeric transcripts in patient tissues
por: Parry, Rhys, et al.
Publicado: (2021)

Formation of $^{117}In-H$ pairs after annealing of GaN implanted with $^{117}Cd(^{117}In)$
por: Dietrich, M, et al.
Publicado: (2001)

Decay study of the $^{117}$Cs and $^{117}$Xe nuclei
por: Marguier, G, et al.
Publicado: (1985)

The reaction $\pi^{+}$ p -> $\omega \delta^{++}$ (1236) at 11.7 GeV/c
por: Evans, D, et al.
Publicado: (1973)

SARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity
por: Meng, Bo, et al.
Publicado: (2022)

Mutations I117V and I117M and Oseltamivir Sensitivity of Pandemic (H1N1) 2009 Viruses
por: Hurt, Aeron C., et al.
Publicado: (2012)

two-prong fitted channels at 11.7 GeV/c
por: Evans, D, et al.
Publicado: (1973)

SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion
por: Mlcochova, Petra, et al.
Publicado: (2021)

Epidemic Spread of SARS-CoV-2 Lineage B.1.1.7 in Brazil
por: Moreira, Filipe R. R., et al.
Publicado: (2021)

SPSC Meeting 69
por: Mannelli, M, et al.
Publicado: (2004)

Tests on helicity conservation in interactions $\pi^{+}$ p at 11.7 GeV/c and $\pi^{-}$ p at 11.2 GeV/c
por: Evans, D, et al.
Publicado: (1973)

Tests on helicity conservation in interactions pi /sup +/p at 117 GeV /c and pi /sup -/p at 112 GeV/c
por: Evans, D, et al.
Publicado: (1973)

High physical work demands have worse consequences for older workers: prospective study of long-term sickness absence among 69 117 employees
por: Andersen, Lars Louis, et al.
Publicado: (2021)

In hospital mortality and short-term outcome of acute ischemic stroke patients contracting SARS CoV-2 infection: Experience from a dedicated stroke unit in Bangladesh
por: Hasibul Hasan, A.T.M.
Publicado: (2021)

First detection of SARS-CoV-2 variant B.1.1.7 in Senegal
por: Padane, A., et al.
Publicado: (2021)

Synonymous Dinucleotide Usage: A Codon-Aware Metric for Quantifying Dinucleotide Representation in Viruses
por: Lytras, Spyros, et al.
Publicado: (2020)

Report of SARS-CoV-2 B1.1.7 Lineage in Morocco
por: Ouadghiri, Mouna, et al.
Publicado: (2021)

Multiorgan tropism of SARS-CoV-2 lineage B.1.1.7
por: Ondruschka, Benjamin, et al.
Publicado: (2021)

Structural Consequences of Variation in SARS-CoV-2 B.1.1.7
por: Ostrov, David A.
Publicado: (2021)

Evaluation of a fully automated high-throughput SARS-CoV-2 multiplex qPCR assay with built-in screening functionality for del-HV69/70- and N501Y variants such as B.1.1.7
por: Nörz, Dominik, et al.
Publicado: (2021)

Community transmission of SARS-CoV-2 with B.1.1.7 lineage in Mumbai, India
por: Shastri, Jayanthi, et al.
Publicado: (2022)

SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern
por: McCallum, Matthew, et al.
Publicado: (2021)

Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England
por: Davies, Nicholas G., et al.
Publicado: (2021)

Cyclin D3 restricts SARS‐CoV‐2 envelope incorporation into virions and interferes with viral spread
por: Gupta, Ravi K, et al.
Publicado: (2022)

Dionysus in 69 /
Publicado: (1970)

Author Correction: SARS-CoV-2 evolution during treatment of chronic infection
por: Kemp, Steven A., et al.
Publicado: (2022)

Emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States
por: Washington, Nicole L., et al.
Publicado: (2021)

Comparison of the Performance of the PanBio COVID-19 Antigen Test in SARS-CoV-2 B.1.1.7 (Alpha) Variants versus non-B.1.1.7 Variants
por: van Ogtrop, M. L., et al.
Publicado: (2021)

Spatiotemporal invasion dynamics of SARS-CoV-2 lineage B.1.1.7 emergence
por: Kraemer, Moritz U. G., et al.
Publicado: (2021)

Clostridium perfringens enterotoxin is a superantigen reactive with human T cell receptors V beta 6.9 and V beta 22
Publicado: (1992)

First Detection of SARS-CoV-2 B.1.1.7 Variant of Concern in an Asymptomatic Dog in Spain
por: Barroso-Arévalo, Sandra, et al.
Publicado: (2021)

Quantification of the spread of SARS-CoV-2 variant B.1.1.7 in Switzerland
por: Chen, Chaoran, et al.
Publicado: (2021)

Tracking of SARS-CoV-2 Alpha variant (B.1.1.7) in Palestine
por: Nasereddin, Abedelmajeed, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_dbsppfkriafjshuuinn48t6npo