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4-OI Attenuates Carbon Tetrachloride-Induced Hepatic Injury via Regulating Oxidative Stress and the Inflammatory Response

The liver is an important metabolic organ, and acute liver injury (ALI) is potentially lethal. Itaconate, a metabolic intermediate from the tricarboxylic acid cycle, showed emerging anti-oxidative and anti-inflammation properties, and an accumulating protective effect in multiple diseases, but its r...

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Detalles Bibliográficos
Autores principales: Li, Ruidong, Yang, Wenchang, Yin, Yuping, Ma, Xianxiong, Zhang, Peng, Tao, Kaixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185275/
https://www.ncbi.nlm.nih.gov/pubmed/34113251
http://dx.doi.org/10.3389/fphar.2021.651444