Dermatan Sulfate Is a Potential Regulator of IgH via Interactions With Pre-BCR, GTF2I, and BiP ER Complex in Pre-B Lymphoblasts

Dermatan sulfate (DS) and autoantigen (autoAg) complexes are capable of stimulating autoreactive CD5+ B1 cells. We examined the activity of DS on CD5+ pre-B lymphoblast NFS-25 cells. CD19, CD5, CD72, PI3K, and Fas possess varying degrees of DS affinity. The three pre-BCR components, Ig heavy chain m...

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Detalles Bibliográficos
Autores principales: Lee, Jongmin, Rho, Jung-hyun, Roehrl, Michael H., Wang, Julia Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185350/
https://www.ncbi.nlm.nih.gov/pubmed/34113352
http://dx.doi.org/10.3389/fimmu.2021.680212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185350/
https://www.ncbi.nlm.nih.gov/pubmed/34113352
http://dx.doi.org/10.3389/fimmu.2021.680212

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