Efficient conversion of human induced pluripotent stem cells into microglia by defined transcription factors

Microglia, the immune cells of the central nervous system, play critical roles in brain physiology and pathology. We report a novel approach that produces, within 10 days, the differentiation of human induced pluripotent stem cells (hiPSCs) into microglia (iMG) by forced expression of both SPI1 and...

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Detalles Bibliográficos
Autores principales: Chen, Shih-Wei, Hung, Yu-Sheng, Fuh, Jong-Ling, Chen, Nien-Jung, Chu, Yeh-Shiu, Chen, Shu-Cian, Fann, Ming-Ji, Wong, Yu-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185376/
https://www.ncbi.nlm.nih.gov/pubmed/33836143
http://dx.doi.org/10.1016/j.stemcr.2021.03.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185376/
https://www.ncbi.nlm.nih.gov/pubmed/33836143
http://dx.doi.org/10.1016/j.stemcr.2021.03.010

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