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Sigma 1 Receptor Modulates Optic Nerve Head Astrocyte Reactivity

PURPOSE: Stimulation of Sigma 1 Receptor (S1R) is neuroprotective in retina and optic nerve. S1R is expressed in both neurons and glia. The purpose of this work is to evaluate the ability of S1R to modulate reactivity responses of optic nerve head astrocytes (ONHAs) by investigating the extent to wh...

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Detalles Bibliográficos
Autores principales: Zhao, Jing, Gonsalvez, Graydon, Bartoli, Manuela, Mysona, Barbara A., Smith, Sylvia B., Bollinger, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185400/
https://www.ncbi.nlm.nih.gov/pubmed/34086045
http://dx.doi.org/10.1167/iovs.62.7.5