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FGF-MAPK signaling regulates human deep-layer corticogenesis

Despite heterogeneity across the six layers of the mammalian cortex, all excitatory neurons are generated from a single founder population of neuroepithelial stem cells. However, how these progenitors alter their layer competence over time remains unknown. Here, we used human embryonic stem cell-der...

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Detalles Bibliográficos
Autores principales: Gantner, Carlos W., Hunt, Cameron P.J., Niclis, Jonathan C., Penna, Vanessa, McDougall, Stuart J., Thompson, Lachlan H., Parish, Clare L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185433/
https://www.ncbi.nlm.nih.gov/pubmed/33836146
http://dx.doi.org/10.1016/j.stemcr.2021.03.014