The chromatin accessibility landscape reveals distinct transcriptional regulation in the induction of human primordial germ cell-like cells from pluripotent stem cells

In vitro induction of human primordial germ cell-like cells (hPGCLCs) provides an ideal platform to recapitulate hPGC development. However, the detailed molecular mechanisms regulating the induction of hPGCLCs remain largely uncharacterized. Here, we profiled the chromatin accessibility and transcri...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoman, Veerapandian, Veeramohan, Yang, Xinyan, Song, Ke, Xu, Xiaoheng, Cui, Manman, Yuan, Weiyan, Huang, Yaping, Xia, Xinyu, Yao, Zhaokai, Wan, Cong, Luo, Fang, Song, Xiuling, Wang, Xiaoru, Zheng, Yi, Hutchins, Andrew Paul, Jauch, Ralf, Liang, Meiyan, Wang, Chenhong, Liu, Zhaoting, Chang, Gang, Zhao, Xiao-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185471/
https://www.ncbi.nlm.nih.gov/pubmed/33930315
http://dx.doi.org/10.1016/j.stemcr.2021.03.032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185471/
https://www.ncbi.nlm.nih.gov/pubmed/33930315
http://dx.doi.org/10.1016/j.stemcr.2021.03.032

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