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HOXA11 plays critical roles in disease progression and response to cytarabine in AML

Lysine methyltransferase 2A (KMT2A, also known as MLL) translocations (MLL-t) are frequently associated with mutations in RAS pathway genes in acute myeloid leukemia (AML). Previous findings with a mouse model showed that cooperation of MLL/AF10 with tyrosine-protein phosphatase non-receptor type 11...

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Detalles Bibliográficos
Autores principales: Fu, Jen-Fen, Shih, Lee-Yung, Yen, Tzung-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185505/
https://www.ncbi.nlm.nih.gov/pubmed/34080665
http://dx.doi.org/10.3892/or.2021.8101