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MAPK4 silencing together with a PARP1 inhibitor as a combination therapy in triple-negative breast cancer cells
Triple-negative breast cancer (TNBC) is the most common type of cancer among females worldwide and is associated with poor prognosis. Poly ADP-ribose polymerase-1 (PARP1) inhibitors are effective against TNBC with mutations in the breast cancer type 1 susceptibility protein (BRCA1) and/or BRCA2 gene...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185508/ https://www.ncbi.nlm.nih.gov/pubmed/34080025 http://dx.doi.org/10.3892/mmr.2021.12187 |