Cargando…

Perampanel, an AMPAR antagonist, alleviates experimental intracerebral hemorrhage-induced brain injury via necroptosis and neuroinflammation

Spontaneous intracerebral hemorrhage (ICH) is a subtype of stroke with high mortality and morbidity due to the lack of effective therapies. The alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist perampanel has been reported to alleviate early brain injury following subarach...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Lixiang, Wang, Yue, Zhang, Can, Cheng, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185517/
https://www.ncbi.nlm.nih.gov/pubmed/34080030
http://dx.doi.org/10.3892/mmr.2021.12183