uPA‐PAI‐1 heteromerization promotes breast cancer progression by attracting tumorigenic neutrophils

High intratumoral levels of urokinase‐type plasminogen activator (uPA)‐plasminogen activator inhibitor‐1 (PAI‐1) heteromers predict impaired survival and treatment response in early breast cancer. The pathogenetic role of this protein complex remains obscure. Here, we demonstrate that heteromerizati...

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Detalles Bibliográficos
Autores principales: Uhl, Bernd, A Mittmann, Laura, Dominik, Julian, Hennel, Roman, Smiljanov, Bojan, Haring, Florian, B Schaubächer, Johanna, Braun, Constanze, Padovan, Lena, Pick, Robert, Canis, Martin, Schulz, Christian, Mack, Matthias, Gutjahr, Ewgenija, Sinn, Peter, Heil, Jörg, Steiger, Katja, Kanse, Sandip M, Weichert, Wilko, Sperandio, Markus, Lauber, Kirsten, Krombach, Fritz, Reichel, Christoph A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185543/
https://www.ncbi.nlm.nih.gov/pubmed/33998175
http://dx.doi.org/10.15252/emmm.202013110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185543/
https://www.ncbi.nlm.nih.gov/pubmed/33998175
http://dx.doi.org/10.15252/emmm.202013110

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