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The WAVE complex associates with sites of saddle membrane curvature

How local interactions of actin regulators yield large-scale organization of cell shape and movement is not well understood. Here we investigate how the WAVE complex organizes sheet-like lamellipodia. Using super-resolution microscopy, we find that the WAVE complex forms actin-independent 230-nm-wid...

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Detalles Bibliográficos
Autores principales: Pipathsouk, Anne, Brunetti, Rachel M., Town, Jason P., Graziano, Brian R., Breuer, Artù, Pellett, Patrina A., Marchuk, Kyle, Tran, Ngoc-Han T., Krummel, Matthew F., Stamou, Dimitrios, Weiner, Orion D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185649/
https://www.ncbi.nlm.nih.gov/pubmed/34096975
http://dx.doi.org/10.1083/jcb.202003086