CD13 inhibition augments DR4-induced tumor cell death in a p-ERK1/2-independent manner

OBJECTIVE: Death receptor 4 (DR4; TRAIL-R1) critically mediates extrinsic apoptosis cascades via binding to TNF-related apoptosis-inducing ligand (TRAIL). However, intrinsic and/or acquired resistance are observed in the clinical application of TRAIL. The aim of this study was to investigate the fun...

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Detalles Bibliográficos
Autores principales: Ni, Jun, Wang, Xiaofei, Shang, Yue, Li, Yi, Chen, Shuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185856/
https://www.ncbi.nlm.nih.gov/pubmed/33710811
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185856/
https://www.ncbi.nlm.nih.gov/pubmed/33710811
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0196

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