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Analysis of the HNF4A isoform-regulated transcriptome identifies CCL15 as a downstream target in gastric carcinogenesis

OBJECTIVE: Hepatocyte nuclear factor 4α (HNF4A) has been demonstrated to be an oncogene in gastric cancer (GC). However, the roles of different HNF4A isoforms derived from the 2 different promoters (P1 and P2) and the underlying mechanisms remain obscure. METHODS: The expression and prognostic value...

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Detalles Bibliográficos
Autores principales: Ni, Zhen, Lu, Wenquan, Li, Qi, Han, Chuan, Yuan, Ting, Sun, Nina, Shi, Yongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185874/
https://www.ncbi.nlm.nih.gov/pubmed/33710810
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0131