Overcoming the UCB HSCs –Derived NK cells Dysfunction through Harnessing RAS/MAPK, IGF-1R and TGF-β Signaling Pathways

BACKGROUND: The natural killer (NK) cells differentiated from umbilical cord blood (UCB) hematopoietic stem cells (HSCs) may be more suitable for cell-based immunotherapy compared to the NK cells from adult donors. This is due to the possibility to choose alloreactive donors and potentially more rob...

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Detalles Bibliográficos
Autores principales: Shokouhifar, Alireza, Anani Sarab, Gholamreza, Yazdanifar, Mahboubeh, Fereidouni, Mohammad, Nouri, Masoumeh, Ebrahimi, Marzieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185927/
https://www.ncbi.nlm.nih.gov/pubmed/34098947
http://dx.doi.org/10.1186/s12935-021-01983-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185927/
https://www.ncbi.nlm.nih.gov/pubmed/34098947
http://dx.doi.org/10.1186/s12935-021-01983-z

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