Redox modifications of cysteine residues regulate the cytokine activity of HMGB1

BACKGROUND: High mobility group box 1 (HMGB1) is a nuclear protein with extracellular inflammatory cytokine activity. It is passively released during cell death and secreted by activated cells of many lineages. HMGB1 contains three conserved redox-sensitive cysteine residues: cysteines in position 2...

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Detalles Bibliográficos
Autores principales: Yang, Huan, Lundbäck, Peter, Ottosson, Lars, Erlandsson-Harris, Helena, Venereau, Emilie, Bianchi, Marco E., Al-Abed, Yousef, Andersson, Ulf, Tracey, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185929/
https://www.ncbi.nlm.nih.gov/pubmed/34098868
http://dx.doi.org/10.1186/s10020-021-00307-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185929/
https://www.ncbi.nlm.nih.gov/pubmed/34098868
http://dx.doi.org/10.1186/s10020-021-00307-1

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