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Redox modifications of cysteine residues regulate the cytokine activity of HMGB1

BACKGROUND: High mobility group box 1 (HMGB1) is a nuclear protein with extracellular inflammatory cytokine activity. It is passively released during cell death and secreted by activated cells of many lineages. HMGB1 contains three conserved redox-sensitive cysteine residues: cysteines in position 2...

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Detalles Bibliográficos
Autores principales:	Yang, Huan, Lundbäck, Peter, Ottosson, Lars, Erlandsson-Harris, Helena, Venereau, Emilie, Bianchi, Marco E., Al-Abed, Yousef, Andersson, Ulf, Tracey, Kevin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185929/ https://www.ncbi.nlm.nih.gov/pubmed/34098868 http://dx.doi.org/10.1186/s10020-021-00307-1

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