Cargando…

Agarose microgel culture delineates lumenogenesis in naive and primed human pluripotent stem cells

Human periimplantation development requires the transformation of the naive pluripotent epiblast into a polarized epithelium. Lumenogenesis plays a critical role in this process, as the epiblast undergoes rosette formation and lumen expansion to form the amniotic cavity. Here, we present a high-thro...

Descripción completa

Detalles Bibliográficos
Autores principales: Schindler, Magdalena, Siriwardena, Dylan, Kohler, Timo N., Ellermann, Anna L., Slatery, Erin, Munger, Clara, Hollfelder, Florian, Boroviak, Thorsten E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185981/
https://www.ncbi.nlm.nih.gov/pubmed/33979603
http://dx.doi.org/10.1016/j.stemcr.2021.04.009