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Agarose microgel culture delineates lumenogenesis in naive and primed human pluripotent stem cells
Human periimplantation development requires the transformation of the naive pluripotent epiblast into a polarized epithelium. Lumenogenesis plays a critical role in this process, as the epiblast undergoes rosette formation and lumen expansion to form the amniotic cavity. Here, we present a high-thro...
Autores principales: | Schindler, Magdalena, Siriwardena, Dylan, Kohler, Timo N., Ellermann, Anna L., Slatery, Erin, Munger, Clara, Hollfelder, Florian, Boroviak, Thorsten E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185981/ https://www.ncbi.nlm.nih.gov/pubmed/33979603 http://dx.doi.org/10.1016/j.stemcr.2021.04.009 |
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