Foxp3 enhancers synergize to maximize regulatory T cell suppressive capacity

T reg cells bearing a diverse antigen receptor repertoire suppress pathogenic T cells and maintain immune homeostasis during their long lifespan. How their robust function is determined genetically remains elusive. Here, we investigate the regulatory space of the cis-regulatory elements of T reg lin...

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Detalles Bibliográficos
Autores principales: Zong, Xinying, Hao, Xiaolei, Xu, Beisi, Crawford, Jeremy Chase, Wright, Shaela, Li, Jun, Zhang, Yang, Bai, Lu, He, Minghong, Jiang, Menglin, Fan, Yiping, Connelly, Jon P., Pruett-Miller, Shondra M., Berns, Hartmut, Janke, Laura, Li, Chunliang, Feng, Yongqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185987/
https://www.ncbi.nlm.nih.gov/pubmed/34086055
http://dx.doi.org/10.1084/jem.20202415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8185987/
https://www.ncbi.nlm.nih.gov/pubmed/34086055
http://dx.doi.org/10.1084/jem.20202415

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