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Lung macrophages drive mucus production and steroid-resistant inflammation in chronic bronchitis

BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) frequently suffer from chronic bronchitis (CB) and display steroid-resistant inflammation with increased sputum neutrophils and macrophages. Recently, a causal link between mucus hyper-concentration and disease progression of CB...

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Detalles Bibliográficos
Autores principales: Andelid, Kristina, Öst, Karolina, Andersson, Anders, Mohamed, Esha, Jevnikar, Zala, Vanfleteren, Lowie E. G. W., Göransson, Melker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186034/
https://www.ncbi.nlm.nih.gov/pubmed/34098956
http://dx.doi.org/10.1186/s12931-021-01762-4