Induction of ferroptosis by ATF3 elevation alleviates cisplatin resistance in gastric cancer by restraining Nrf2/Keap1/xCT signaling

BACKGROUND: Currently, resistance against cisplatin (DDP) is a frequent problem for the success of advanced gastric carcinoma (GC) chemotherapy. Here, we sought to investigate the function of activating transcription factor 3 (ATF3) n GC chemoresistance. METHODS: Expression of ATF3 was determined in...

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Detalles Bibliográficos
Autores principales: Fu, Dazhi, Wang, Chunxiao, Yu, Lei, Yu, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186082/
https://www.ncbi.nlm.nih.gov/pubmed/34098867
http://dx.doi.org/10.1186/s11658-021-00271-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186082/
https://www.ncbi.nlm.nih.gov/pubmed/34098867
http://dx.doi.org/10.1186/s11658-021-00271-y

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