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Altered DNA methylation pattern reveals epigenetic regulation of Hox genes in thoracic aortic dissection and serves as a biomarker in disease diagnosis

BACKGROUND: Thoracic aortic dissection (TAD) is a severe disease with limited understandings in its pathogenesis. Altered DNA methylation has been revealed to be involved in many diseases etiology. Few studies have examined the role of DNA methylation in the development of TAD. This study explored a...

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Detalles Bibliográficos
Autores principales: Liu, Peiru, Zhang, Jing, Du, Duo, Zhang, Dandan, Jin, Zelin, Qiu, Wenqing, Zhou, Xiushi, Dong, Shulong, Zhou, Mengyu, Zhao, Heyu, Zhang, Wei, Ma, Jiakang, Sun, Shaoyang, Fu, Weiguo, Liu, Yun, Wang, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186232/
https://www.ncbi.nlm.nih.gov/pubmed/34103071
http://dx.doi.org/10.1186/s13148-021-01110-9