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PiggyBac-Generated CAR19-T Cells Plus Lenalidomide Cause Durable Complete Remission of Triple-Hit Refractory/Relapsed DLBCL: A Case Report

MYC/BCL2/BCL6 triple-hit lymphoma (THL) is an uncommon subset of high-grade B-cell lymphoma with aggressive clinical behavior and poor prognosis. TP53 mutation is an independently poor progonistic indicator in patients with THL, hence novel therapeutic strategies are needed for these patients. CD19-...

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Detalles Bibliográficos
Autores principales: Li, Chenggong, Sun, Yan, Wang, Jing, Tang, Lu, Jiang, Huiwen, Guo, Tao, Liu, Lin, Wu, Yaohui, Ai, Lisha, Xia, Linghui, Wu, Jianjun, Lin, Zhicai, Qian, Qijun, Hu, Yu, Mei, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186315/
https://www.ncbi.nlm.nih.gov/pubmed/34113336
http://dx.doi.org/10.3389/fimmu.2021.599493