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Enhancement of the Tolerogenic Phenotype in the Liver by ImmTOR Nanoparticles

ImmTOR biodegradable nanoparticles encapsulating rapamycin have been shown to induce a durable tolerogenic immune response to co-administered biologics and gene therapy vectors. Prior mechanism of action studies have demonstrated selective biodistribution of ImmTOR to the spleen and liver following...

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Detalles Bibliográficos
Autores principales: Ilyinskii, Petr O., Roy, Christopher J., LePrevost, Julie, Rizzo, Gina L., Kishimoto, Takashi Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186318/
https://www.ncbi.nlm.nih.gov/pubmed/34113339
http://dx.doi.org/10.3389/fimmu.2021.637469