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Enhancement of the Tolerogenic Phenotype in the Liver by ImmTOR Nanoparticles
ImmTOR biodegradable nanoparticles encapsulating rapamycin have been shown to induce a durable tolerogenic immune response to co-administered biologics and gene therapy vectors. Prior mechanism of action studies have demonstrated selective biodistribution of ImmTOR to the spleen and liver following...
Autores principales: | Ilyinskii, Petr O., Roy, Christopher J., LePrevost, Julie, Rizzo, Gina L., Kishimoto, Takashi Kei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186318/ https://www.ncbi.nlm.nih.gov/pubmed/34113339 http://dx.doi.org/10.3389/fimmu.2021.637469 |
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