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Immunomics-Guided Antigen Discovery for Praziquantel-Induced Vaccination in Urogenital Human Schistosomiasis

Despite the enormous morbidity attributed to schistosomiasis, there is still no vaccine to combat the disease for the hundreds of millions of infected people. The anthelmintic drug, praziquantel, is the mainstay treatment option, although its molecular mechanism of action remains poorly defined. Pra...

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Detalles Bibliográficos
Autores principales: Pearson, Mark S., Tedla, Bemnet A., Becker, Luke, Nakajima, Rie, Jasinskas, Al, Mduluza, Takafira, Mutapi, Francisca, Oeuvray, Claude, Greco, Beatrice, Sotillo, Javier, Felgner, Philip L., Loukas, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186320/
https://www.ncbi.nlm.nih.gov/pubmed/34113343
http://dx.doi.org/10.3389/fimmu.2021.663041