MicroRNA-92b augments sorafenib resistance in hepatocellular carcinoma via targeting PTEN to activate PI3K/AKT/mTOR signaling

Sorafenib (SOR) resistance is still a significant challenge for the effective treatment of hepatocellular carcinoma (HCC). The mechanism of sorafenib resistance remains unclear. Several microRNAs (miRNAs) have been identified as playing a role in impairing the sensitivity of tumor cells to treatment...

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Detalles Bibliográficos
Autores principales: Cheng, Zhouyang, Ni, Qingfeng, Qin, Lei, Shi, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186377/
https://www.ncbi.nlm.nih.gov/pubmed/34076140
http://dx.doi.org/10.1590/1414-431X2020e10390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186377/
https://www.ncbi.nlm.nih.gov/pubmed/34076140
http://dx.doi.org/10.1590/1414-431X2020e10390

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