The Bidirectional Relationship Between Cancer Epigenetics and Metabolism

Metabolic and epigenetic reprogramming are characteristics of cancer cells that, in many cases, are linked. Oncogenic signaling, diet, and tumor microenvironment each influence the availability of metabolites that are substrates or inhibitors of epigenetic enzymes. Reciprocally, altered expression o...

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Detalles Bibliográficos
Autores principales: Izzo, Luke T., Affronti, Hayley C., Wellen, Kathryn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186467/
https://www.ncbi.nlm.nih.gov/pubmed/34109280
http://dx.doi.org/10.1146/annurev-cancerbio-070820-035832