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The Bidirectional Relationship Between Cancer Epigenetics and Metabolism
Metabolic and epigenetic reprogramming are characteristics of cancer cells that, in many cases, are linked. Oncogenic signaling, diet, and tumor microenvironment each influence the availability of metabolites that are substrates or inhibitors of epigenetic enzymes. Reciprocally, altered expression o...
Autores principales: | Izzo, Luke T., Affronti, Hayley C., Wellen, Kathryn E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186467/ https://www.ncbi.nlm.nih.gov/pubmed/34109280 http://dx.doi.org/10.1146/annurev-cancerbio-070820-035832 |
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