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Spatial distribution of lamin A/C determines nuclear stiffness and stress-mediated deformation
While diverse cellular components have been identified as mechanotransduction elements, the deformation of the nucleus itself is a critical mechanosensory mechanism, implying that nuclear stiffness is essential in determining responses to intracellular and extracellular stresses. Although the nuclea...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8186481/ https://www.ncbi.nlm.nih.gov/pubmed/34028539 http://dx.doi.org/10.1242/jcs.248559 |