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Histone Deacetylase 2 Suppresses Skeletal Muscle Atrophy and Senescence via NF-κB Signaling Pathway in Cigarette Smoke-Induced Mice with Emphysema

BACKGROUND: Exposure to cigarette smoke (CS) is the main risk factor for chronic obstructive pulmonary disease (COPD). CS not only causes chronic airway inflammation and lung damage but also is involved in skeletal muscle dysfunction (SMD). Previous studies have shown that histone deacetylase 2 (HDA...

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Detalles Bibliográficos
Autores principales: Li, Chao, Deng, Zhaohui, Zheng, Guixian, Xie, Ting, Wei, Xinyan, Huo, Zengyu, Bai, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187003/
https://www.ncbi.nlm.nih.gov/pubmed/34113097
http://dx.doi.org/10.2147/COPD.S314640