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PU.1 Mimic Synthetic Peptides Selectively Bind with GATA-1 and Allow c-Jun PU.1 Binding to Enhance Myelopoiesis

BACKGROUND: Hematopoietic stem cells' commitment to myelopoiesis builds immunity to prevent infection. This process is controlled through transcription factor, especially Purine rich box 1 (PU.1) protein, which plays a central role in regulating myelopoiesis. The β3/β4 region of PU.1 accommodat...

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Detalles Bibliográficos
Autores principales: Raghav, Pawan Kumar, Gangenahalli, Gurudutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187006/
https://www.ncbi.nlm.nih.gov/pubmed/34113102
http://dx.doi.org/10.2147/IJN.S303235