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Limited Impact of 6-Mercaptopurine on Inflammation-Induced Chemokines Expression Profile in Primary Cultures of Enteric Nervous System

Increasing evidences indicate that the enteric nervous system (ENS) and enteric glial cells (EGC) play important regulatory roles in intestinal inflammation. Mercaptopurine (6-MP) is a cytostatic compound clinically used for the treatment of inflammatory bowel diseases (IBD), such as ulcerative coli...

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Detalles Bibliográficos
Autores principales: Kneusels, Jan, Kaehler, Meike, Cascorbi, Ingolf, Wedel, Thilo, Neunlist, Michel, Lucius, Ralph, Cossais, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187225/
https://www.ncbi.nlm.nih.gov/pubmed/33864170
http://dx.doi.org/10.1007/s11064-021-03324-y