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Nanoscale architecture of a VAP-A-OSBP tethering complex at membrane contact sites
Membrane contact sites (MCS) are subcellular regions where two organelles appose their membranes to exchange small molecules, including lipids. Structural information on how proteins form MCS is scarce. We designed an in vitro MCS with two membranes and a pair of tethering proteins suitable for cryo...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187361/ https://www.ncbi.nlm.nih.gov/pubmed/34103503 http://dx.doi.org/10.1038/s41467-021-23799-1 |