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Nanoscale architecture of a VAP-A-OSBP tethering complex at membrane contact sites

Membrane contact sites (MCS) are subcellular regions where two organelles appose their membranes to exchange small molecules, including lipids. Structural information on how proteins form MCS is scarce. We designed an in vitro MCS with two membranes and a pair of tethering proteins suitable for cryo...

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Detalles Bibliográficos
Autores principales: de la Mora, Eugenio, Dezi, Manuela, Di Cicco, Aurélie, Bigay, Joëlle, Gautier, Romain, Manzi, John, Polidori, Joël, Castaño-Díez, Daniel, Mesmin, Bruno, Antonny, Bruno, Lévy, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187361/
https://www.ncbi.nlm.nih.gov/pubmed/34103503
http://dx.doi.org/10.1038/s41467-021-23799-1