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Accessory proteins of the RAS-MAPK pathway: moving from the side line to the front line

Health and disease are directly related to the RTK-RAS-MAPK signalling cascade. After more than three decades of intensive research, understanding its spatiotemporal features is afflicted with major conceptual shortcomings. Here we consider how the compilation of a vast array of accessory proteins m...

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Detalles Bibliográficos
Autores principales: Pudewell, Silke, Wittich, Christoph, Kazemein Jasemi, Neda S., Bazgir, Farhad, Ahmadian, Mohammad R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187363/
https://www.ncbi.nlm.nih.gov/pubmed/34103645
http://dx.doi.org/10.1038/s42003-021-02149-3