Cargando…

The zinc-finger protein Red1 orchestrates MTREC submodules and binds the Mtl1 helicase arch domain

Cryptic unstable transcripts (CUTs) are rapidly degraded by the nuclear exosome in a process requiring the RNA helicase Mtr4 and specific adaptor complexes for RNA substrate recognition. The PAXT and MTREC complexes have recently been identified as homologous exosome adaptors in human and fission ye...

Descripción completa

Detalles Bibliográficos
Autores principales: Dobrev, Nikolay, Ahmed, Yasar Luqman, Sivadas, Anusree, Soni, Komal, Fischer, Tamás, Sinning, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187409/
https://www.ncbi.nlm.nih.gov/pubmed/34103492
http://dx.doi.org/10.1038/s41467-021-23565-3