G-MDSCs promote aging-related cardiac fibrosis by activating myofibroblasts and preventing senescence

Aging is one of the most prominent risk factors for heart failure. Myeloid-derived suppressor cells (MDSCs) accumulate in aged tissue and have been confirmed to be associated with various aging-related diseases. However, the role of MDSCs in the aging heart remains unknown. Through RNA-seq and bioch...

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Detalles Bibliográficos
Autores principales: Sun, Shu-Ning, Ni, Shi-Hao, Li, Yue, Liu, Xin, Deng, Jian-Ping, Chen, Zi-Xin, Li, Huan, Feng, Wen-Jun, Huang, Yu-Sheng, Li, Da-Nian, Xian, Shao-Xiang, Yang, Zhong-Qi, Wang, Ling-Jun, Lu, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187421/
https://www.ncbi.nlm.nih.gov/pubmed/34103476
http://dx.doi.org/10.1038/s41419-021-03874-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187421/
https://www.ncbi.nlm.nih.gov/pubmed/34103476
http://dx.doi.org/10.1038/s41419-021-03874-7

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