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PB01 suppresses radio-resistance by regulating ATR signaling in human non-small-cell lung cancer cells

Despite the common usage of radiotherapy for the treatment of human non-small-cell lung cancer (NSCLC), cancer therapeutic efficacy and outcome with ionizing radiation remains a challenge. Here, we report the antitumor effects and mechanism of a novel benzothiazole derivative PB01 (4-methoxy-cyclohe...

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Detalles Bibliográficos
Autores principales: Kim, Tae Woo, Hong, Da-Won, Hong, Sung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187425/
https://www.ncbi.nlm.nih.gov/pubmed/34103635
http://dx.doi.org/10.1038/s41598-021-91716-z