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Genetic dependency of Alzheimer’s disease-associated genes across cells and tissue types

Effective treatments targeting disease etiology are urgently needed for Alzheimer’s disease (AD). Although candidate AD genes have been identified and altering their levels may serve as therapeutic strategies, the consequence of such alterations remain largely unknown. Herein, we analyzed CRISPR kno...

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Detalles Bibliográficos
Autores principales: Jaladanki, Suraj K., Elmas, Abdulkadir, Malave, Gabriel Santos, Huang, Kuan-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187448/
https://www.ncbi.nlm.nih.gov/pubmed/34103633
http://dx.doi.org/10.1038/s41598-021-91713-2