Sugar phosphate activation of the stress sensor eIF2B

The multi-subunit translation initiation factor eIF2B is a control node for protein synthesis. eIF2B activity is canonically modulated through stress-responsive phosphorylation of its substrate eIF2. The eIF2B regulatory subcomplex is evolutionarily related to sugar-metabolizing enzymes, but the bio...

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Detalles Bibliográficos
Autores principales: Hao, Qi, Heo, Jin-Mi, Nocek, Boguslaw P., Hicks, Kevin G., Stoll, Vincent S., Remarcik, Clint, Hackett, Sean, LeBon, Lauren, Jain, Rinku, Eaton, Dan, Rutter, Jared, Wong, Yao Liang, Sidrauski, Carmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187479/
https://www.ncbi.nlm.nih.gov/pubmed/34103529
http://dx.doi.org/10.1038/s41467-021-23836-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187479/
https://www.ncbi.nlm.nih.gov/pubmed/34103529
http://dx.doi.org/10.1038/s41467-021-23836-z

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