Cargando…

Regulatory properties of vitronectin and its glycosylation in collagen fibril formation and collagen-degrading enzyme cathepsin K activity

Vitronectin (VN) is a glycoprotein found in extracellular matrix and blood. Collagen, a major extracellular matrix component in mammals, is degraded by cathepsin K (CatK), which is essential for bone resorption under acidic conditions. The relationship between VN and cathepsins has been unclear. We...

Descripción completa

Detalles Bibliográficos
Autores principales: Date, Kimie, Sakagami, Hiromi, Yura, Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187593/
https://www.ncbi.nlm.nih.gov/pubmed/34103584
http://dx.doi.org/10.1038/s41598-021-91353-6