Quinacrine directly dissociates amyloid plaques in the brain of 5XFAD transgenic mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) is the most common type of dementia characterized by the abnormal accumulation of amyloid-β (Aβ) in the brain. Aβ misfolding is associated with neuroinflammation and synaptic dysfunction, leading to learning and memory deficits. Therefore, Aβ production and aggregation have...

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Detalles Bibliográficos
Autores principales: Park, Sohui, Kim, Hye Yun, Oh, Hyun-A, Shin, Jisu, Park, In Wook, Yoon, Soljee, Woo, Dong Ho, Kim, YoungSoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187640/
https://www.ncbi.nlm.nih.gov/pubmed/34103615
http://dx.doi.org/10.1038/s41598-021-91563-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187640/
https://www.ncbi.nlm.nih.gov/pubmed/34103615
http://dx.doi.org/10.1038/s41598-021-91563-y

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