Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank

To identify candidate causal genes of asthma, we performed a genome-wide association study (GWAS) in UK Biobank on a broad asthma definition (n = 56,167 asthma cases and 352,255 controls). We then carried out functional mapping through transcriptome-wide association studies (TWAS) and Mendelian rand...

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Detalles Bibliográficos
Autores principales: Valette, Kim, Li, Zhonglin, Bon-Baret, Valentin, Chignon, Arnaud, Bérubé, Jean-Christophe, Eslami, Aida, Lamothe, Jennifer, Gaudreault, Nathalie, Joubert, Philippe, Obeidat, Ma’en, van den Berge, Maarten, Timens, Wim, Sin, Don D., Nickle, David C., Hao, Ke, Labbé, Catherine, Godbout, Krystelle, Côté, Andréanne, Laviolette, Michel, Boulet, Louis-Philippe, Mathieu, Patrick, Thériault, Sébastien, Bossé, Yohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187656/
https://www.ncbi.nlm.nih.gov/pubmed/34103634
http://dx.doi.org/10.1038/s42003-021-02227-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187656/
https://www.ncbi.nlm.nih.gov/pubmed/34103634
http://dx.doi.org/10.1038/s42003-021-02227-6

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